Our succes in integrating information into models that generate unique insights, allowing executives to make better drug development decisions, is reflected in our gold-standard research publications.
Latest publications
Population pharmacokinetics and exposure-response relationships of dostarlimab in primary advanced or recurrent endometrial cancer in part 1 of RUBY | Oncology
Kuchimanchi M
, Jorgensen TL
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qP contributors: Hanze E, Alskar O |
2025|
Journal|
British Journal of Clinical Pharmacology
Link
Exposure-response relationships of mirvetuximab soravtansine in patients with folate receptor-alpha-positive ovarian cancer: Justification of therapeutic dose regimen | Oncology
Tu YP
, Lagraauw HM
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qP contributors: Lagraauw HM, Hanze E |
2025|
Journal|
British Journal of Clinical Pharmacology
Link
Results of the first-in-human, randomized, double-blind, placebo-controlled, single- and multiple-ascending dose study of BIIB113 in healthy volunteers | CNS
Nery FC
et al.
|
qP contributors: Suttle B |
2025|
Journal|
The Journal of Prevention of Alzheimer's Disease
Link
Population Pharmacokinetics of Atogepant for the Prevention of Migraine | CNS
Schlachter L
et al.
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qP contributors: Voelkner A; Jonsson F; Lagraauw HM |
2025|
Journal|
Clinical Pharmacokinetics
Link
A minimal physiologically-based pharmacokinetic modeling platform to predict intratumor exposure and receptor occupancy of an anti-LAG-3 monoclonal antibody | Oncology
Michelet R
, Petersson K
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qP contributors: Michelet R, Petersson K |
2024|
Journal|
CPT: Pharmacometrics & Systems Pharmacology
Link
A Phase I Study of the Pharmacokinetics, Pharmacodynamics, and Safety of Liposomal Bupivacaine for Sciatic Nerve Block in the Popliteal Fossa for Bunionectomy | Analgesia
Sessler DI
, Bao X
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qP contributors: Voelkner A |
2024|
Journal|
Journal of Clinical Pharmacology
Link
Modeling and Simulations in Latin-American Generic Markets: Perspectives from Chilean Local Industry, Regulatory Agency, and Academia | All
Personalized Dosing of Medicines for Children: A Primer on Pediatric Pharmacometrics for Clinicians | Pediatrics
Phase 1, placebo-controlled, single ascending dose trial to evaluate the safety, pharmacokinetics and effect on altered states of consciousness of intranasal BPL-003 (5-methoxy-N,N-dimethyltryptamine benzoate) in healthy participants | CNS
Rucker JJ
, Roberts C
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qP contributors: Suttle B |
2024|
Journal|
Journal of Psychopharmacology
Link
A population pharmacokinetics model of balovaptan to support dose selection in adult and pediatric populations | Pediatrics
Schaedeli Stark F
, Chavanne C
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qP contributors: Jolling K, Lagraauw HM, Lindbom L, Prins K |
2024|
Journal|
Journal of Pharmacokinetics and Pharmacodynamics
Link